May 10, 2010

PhD Research Fellow in Biophysics and Medical Physics, University of Oslo, Norway

The Department og Physics has experimental as well as theoretical research activities in a broad range of subfields (see http://www.physics.uio.no/research/), with a stated ambition of attaining excellence in its main fields of research. At the department there is a scientific staff of 47 tenured positions, 8 adjunct professors, and 21 fellowships for PhD-students. In addition there are 52 temporary positions based on external financing. There is a technical/administrative staff of 38 persons. The teaching at the department is related to the degrees of bachelor, master and PhD, currently with about 125 master- and 75 PhD students. For more information please see www.fys.uio.no.

The fellowship is for a period of up to 4 years, with 25 % compulsory work. The teaching must be conducted in one of the Scandinavian languages or English. Starting date no later than 1 October, 2010.

Job description:

The position will be associated with the Biophysics and Medical Physics (BMF) research group. The activities in this group are centered on biological effects of ionizing radiation. Ionizing radiation is widely used in medicine, research and industry. To fully understand radiation actions at different levels of molecular and cellular organization, knowledge of radiation induced free radical structures and their formation mechanisms are of fundamental importance. By combining low-temperature electron paramagnetic resonance (EPR) experiments and density functional theory (DFT) calculations the initially formed species may be identified.

The BMF-group is uniquely equipped with experimental facilities allowing low temperature X-irradiation and in-situ EPR experiments. The laboratory collaborates closely with universities in Belgium and USA on a project: Mechanistic aspects of the transformation from initial radicals to stable products. Radiation-induced processes in solid sugars are studied theoretically and experimentally to gain insight into the role of the deoxyribose unit in the radiation chemistry of DNA. Theoretically, calculations are done using Gaussian09 in cluster (ONIOM) models by DFT and TDDFT; and periodical calculations are made using the program package CP2K. Experimentally, end products are measured by electron magnetic resonance experiments with the initial irradiation being performed at 4 K. One goal of this project is to identify which conditions are required for experimentally observing proton transfer processes and/or dissociative electron capture, as well as mechanisms and energetics of the subsequent radical reactions.

The successful Research Fellow is expected to contribute significantly to the theoretical side in this project.

Applicants may submit a project proposal for the qualifying work during the program. The project proposal should include research topic, main issues, as well as choice of theory and method.

Requirements:

Applicants must hold a Master's degree or equivalent in physics is required.

The candidate will have a comprehensive background in DFT (cluster and periodical) and TD-DFT calculations on biomolecular organic free radicals and should have documented knowledge within general radiation physics and chemistry. Documented knowledge of magnetic resonance spectroscopy (in particular EPR) is required.

The purpose of the fellowship is research training leading to the successful completion of a PhD degree.

The fellowship requires admission to the research training programme at the Faculty of Mathematics and Natural Sciences. An approved plan for the research training, including a project outline, must be submitteed no later than two months after taking up the position, and the admission must be approved within three months. For more information see: http://www.uio.no/admhb/reglhb/personal/tilsettingvitenskapelig/regulationstermcondition.xml

A good command of English is required of all students attending the University of Oslo.
http://www.matnat.uio.no/english/research/education/proficiency_in_English.html

Salary:

PhD Research Fellow (SKO 1017), pay grade: 45-51 (NOK 355 400 – 394 200 per year, depending on seniority/qualifications)

The application must include:

Application letter
CV (summarizing education, positions and academic work - scientific publications)
Copies of educational certificates, transcript of records and letters of recommendation
List of publications and academic work that the applicant wishes to be considered by the evaluation committee
Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number)
Foreign applicants are advised to attach an explanation of their University’s grading system. Please remember that all documents should be in English or a Scandinavian language.

Closing date for applications: 15 May, 2010

The University of Oslo has an agreement for all employees, aiming to secure rights to research results a.o.

The University of Oslo has a goal of recruiting more women in academic positions. Women are encouraged to apply.

The University of Oslo also has a goal of recruiting ethnic minorities to Norway in academic positions. Ethnic minorities are encouraged to apply.

Please quote 10 Academic Resources Daily in your application to this opportunity!

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