Jan 12, 2010

Post-doctoral : Scientist Safety Pharmacology (Cardiovascular)


Scientist Safety Pharmacology (Cardiovascular) Two-year post Competitive salary + benefits AlderleyPark, Cheshire

Here´s a great opportunity to develop your expertise within a committed and recognised scientific team.

About the role
We are looking for a post-doctoral scientist to join our Safety Pharmacology team for two years, to support a project addressing translation from preclinical to
clinical models. The project aims to evaluate and improve the predictive value of preclinical cardiac investigations, with a special focus on QRS prolongation as a marker of pro- arrhythmic risk.

Your work will potentially influence the preclinical strategies that are already in place within Global Safety Pharmacology, as well as the risk assessment of candidate drugs before the first clinical trials. For that reason, you can expect to be directly involved in different preclinical models, from in-vitro screens up to in-vivo telemetry studies. It is anticipated that the work will lead to scientific publication, influencing both the drug selection process and the scientific community.

About you
PhD qualified, you will ideally hold a UK personal licence for animal experimentation. While a background in cardiovascular pharmacology or toxicology would be ideal, we´re equally interested in any competence relating to the
late phases of pre-clinical development. You will also need technical and scientific skills in both in-vitro and in-vivo electrophysiology, with broad knowledge of
preclinical risk assessment.

About us
As one of the world´s leading pharmaceutical companies, AstraZeneca is focused on
providing innovative, effective medicines that make a real difference in key
areas of healthcare. With 66,000 staff around the world, we invest $16 million every working day on research and development. For full details please click or visit:
quoting ref: SAUK113.

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