A Post-doctoral Position, awarded by Thev Leducq Foundation, is immediately available at the INSERM-UPMC (University Pierre & Marie Curie)-Paris VI, Hôpital Pitié-Salpêtriè re, in a dynamic research group highly interested in cardiac cell membrane expression of ion channels. The lab is localized in center Paris.
The Project: Our group is conducting fundamental research to characterize the development and electrophysiological consequences of cardiac heterogeneity at the
molecular, cellular and tissue levels, in the context of cardiac arrhythmias. Many study axis are currently investigated, such as the roles of protein partners specialized in the anchoring and the targeting of ion channels (Circ Res. 2009 27;104(6):758- 69.) and the role of vesicle trafficking in the control of ion channels in the cell membrane (Proc Natl Acad Sci U S A. 2009 25;106(34):14681- 6).
The successful candidate will be a skillful and extremely motivated scientist with a PhD. She/he must have a strong background in physiology, and cellular and molecular
electrophysiology, but, must deal easily with the biochemistry of membrane proteins, cell biology and molecular biology. The applicant will be involved in collaborations with other members of the group and must show a high motivation to interdisciplinary work. He may also possess knowledge and experience of another excitable tissue than the heart. He will have the opportunity to use different type of imagery tools such
as confocal, 3-D deconvolution microscopes, run FRAP experiments and participate to the development of TIRF (Total Internal Reflection Fluorescence) microscopy and videomicroscopy.
Applications, including a curriculum vitae and contact details for at least two references should be sent by e-mail to: stephen.hatem@ upmc.fr.
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