PhD Studentship The use of hormone replacement therapy (HRT) and associated risks
Postgraduate Medical School, Department of Pharmacoepidemiolog y
*Project supervisors: Dr CS de Vries, Professor RDT Farmer, Dr JC Stevenson*
Applications are invited from suitably qualified graduates (2:1 or above) for a full-time PhD studentship to work on the efficacy and safety of hormone replacement therapy (HRT). HRT has been used widely for the relief of menopausal symptoms and the prevention and treatment of post-menopausal osteoporosis. Publication and interpretation of results from the Women's Health Initiative (WHI) and the Million Women Study (MWS), however, has created uncertainty about the safety of HRT amongst both clinicians and patients. The successful applicant will use data from the General Practice Research Database in an epidemiological study to describe the use of HRT, its efficacy and associated risks. There will be a particular focus on how
the use of HRT affects the risk of acute myocardial infarction and breast cancer.
The successful applicant will be registered for a PhD (MPhil in the first instance) in the Postgraduate Medical School, University of Surrey. The studentship is available for three years and provides a postgraduate stipend starting from £12,500 per annum.
The post will be based in the Department of Pharmacoepidemiolog y at the University of Surrey's Postgraduate Medical School (PGMS), a research-led facility for translational medical research and postgraduate teaching. The successful applicant will work under the day-to-day supervision of the Head of Department (Dr C de Vries) and in close collaboration with Professor Farmer and Dr Stevenson. Potential applicants should note that this PhD studentship is research-based and a capacity and aptitude for independent learning is essential. The work will involve epidemiological design and analysis of a relational medical database and therefore, prior experience with data manipulation in relational database management programmes such as Microsoft Access is advantageous. The successful applicant will be expected
to submit research work for publication and for presentation at national and international conferences and to be available to travel within or outside the UK as necessary. In addition, the successful applicant will contribute to and participate in the Department's in-house training program (teaching sessions, journal club).
PGMS achieved a 5*A rating in the 2001 Research Assessment Exercise (RAE). The Department of Pharmacoepidemiolog y has a well-established international reputation for its research in drug safety.
Informal enquiries may be addressed to Dr C de Vries:
c.de-vries@surrey. ac.uk, +44 1483 688594
Applications should be submitted on the Research Degree application form and submitted by 4 January 2007.
A copy of the form can be found at
http://surrey. ac.uk/pgstudy/ research. pdftogether with guidance notes
at
http://surrey. ac.uk/pgstudy/ guidanceresearch .pdf. Applications (with a covering letter outlining your research/scientific interests, a detailed CV, a transcript of your degree(s) and the names and addresses of three referees) should be sent to:
Dr C de Vries
Head, Department of Pharmacoepidemiolog y
Postgraduate Medical School (E5)
Daphne Jackson Road
Manor Park
Guildford
GU2 7WG
Email: c.de-vries@surrey. ac.uk
*Closing date: 4 January 2007; interviews will be held on 16 January 2007*
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