PhD in Biological Physics
Modeling The Mitotic Spindle
European Molecular Biology Laboratory, Heidelberg, Germany.
Eukaryotic cells are the building blocks of multi-cellular life. Their genetic material is stored on discrete entities: the chromosomes, which must be segregated to the daughter cells at each division. This essential task is accomplished with high fidelity by the mitotic spindle, a remarkable example of dynamic intracellular structure. A PhD fellowship financed by HFSP is available in the laboratory of F.
Nédélec, to study the mitotic spindle using the tools of biophysics, modeling and numerical simulations. The work will be conducted in collaboration with the experimental laboratories of Arshad Desai (Ludwig cancer research institute, San Diego, USA).
We proposed to initially study the chromosomes alignment in spindle of C. elegans. We will study further aspects of microtubule- chromosome interactions in divergent organisms, to uncover universal mechanisms of mitotic spindle function. The work will involve advanced optical microscopy, mathematical modeling, and will require traveling to San Diego.
Applicants with prior training in Physics, Mathematics, I.T. or engineering, and a willingness to explore the opportunities offered in Biology are encouraged to apply. EMBL is a renowned international research laboratory, with more than 60 nationalities represented. The working language is English.
The deadline for application is November 1st, 2006.
To apply online: www.embl.de/ training/ phdprogramme
Important: select Cell Biology and Biophysics in your `Programme preference'
For more information: www.cytosim. org
François Nédélec, BioMS Group leader
EMBL, Cell Biology and Cell Biophysics
Meyerhofstrasse 1, 69117 Heidelberg, Germany
Email: nedelec@embl. de
Telephone: (+49) 6221 387 597
Telefax: (+49) 6221 387 512
[sursa beasiswa]
