The project will focus on the basic principles of disintegrin- metalloproteinas es (ADAMs) in the biology and pathology of the skin, especially on skin blistering, re-epithelization and skin cancer development. We will use conditional and constitutive ADAM knockout mice to reveal principle malfunctions. Further validation of biological functions will be performed by cell culture and mouse models.
The PhD student will use a broad spectrum of molecular biological and protein chemical methods, including confocal microscopy, video imaging, DNA chip arrays. Salary is according to TVL (E13/2).
Successful applicants should have a background in molecular biology, biochemistry, or related disciplines. Ideally the candidate has experience in molecular biology, cell biology, protein biochemistry and/or histology/pathology . If you are highly motivated and interested in a thesis project which offers the opportunity to acquire new skills in an international team, please send your application including a
letter of motivation, your CV and two references preferentially via e-mail until 15. December 2009 to Dr. Claus-Werner Franzke; Department of Dermatology, University Medical Center Freiburg, Haupstr. 7, 79104 Freiburg, E-mail: claus-werner. franzke@uniklini k-freiburg. de
Please quote 10 Academic Resources Daily in your application to this opportunity!