Oct 2, 2006

PhD Studentship in Enzyme Technology at Institute for Cell and Molecular Biosciences, Newcastle University

DTI/Unilever- funded three year Ph.D studentship in Enzyme Technology
A three year DTI-funded Ph.D studentship is available in the Laboratory of Professor Harry Gilbert in the Institute for Cell and Molecular Biosciences, Newcastle University. The project, which is in collaboration with Unilever, will focus on developing novel recombinant enzymes for use in a number of industrial processes including the detergent industry. The student will employ a combination of rational design, forced protein evolution and module swapping to generate novel enzymes whose stability and catalytic properties will be extensively analyzed both in vitro and within an industrial context. The studentship will provide the successful applicant with experience in molecular biology, enzymology, structural biology and in the design of biocatalysts for a variety of industrial processes. Although not formally a CASE studentship, the student will have the opportunity to work at Unilever and will receive a stipend of £14,000 per year.

Examples of ongoing research, relevant to this studentship, in Professor Gilbert`s laboratory are provided in the following references. Proctor et al. (2005) Proc. Natl. Acad. Sci. USA 102, 2697-702; Flint et al. (2005) Nature Structural Biology and Molecular Biology 12, 608-14. McCartney et al. (2006) Proc. Natl. Acad. Sci. USA 103, 4765-70; Carvalho et al. (2003) Proc. Natl. Acad. Sci. USA 100, 13809-14.

Please contact Professor Gilbert (H.J.Gilbert@ ncl.ac.uk) for further information.

Applicants, who are expected to have at least an upper second (or equivalent) in a biologically or chemically-based subject should send their CV and the names of two academic referees directly to Professor Gilbert via e.mail. The studentship is available from October 1st 2006 onwards.

N.B. This studentship is open to all nationalities

Further details please see http://www.ncl. ac.uk/camb/ postgrad/ studentship/

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